Alzheimer-dementia, is a disorder which results from loss of mental functions with aging. Memory loss, forgetfulness is the most obvious complaint.
Memory is a brain function that allows each activity learned to be recorded first and then recalled from the memory for an extended period of time. Near (close) memory, middle memory and remote memory can be defined.
Near memory contains knowledge occurnig in minutes while middle in days and remote memory recalls events happened years before.
Close memory is affected in most of the Alzheimer's disease first. The patient's complaints are primarily related to nearby memory. The oldest and most powerful recorded information can be stored until the end of life if there is no Alzheimer's or similar disease that holds the brain.
Distinct forgetfulness, closure, silence or restlessness, sleeping disorder, obsession, deletion of frequently repeated events, mixing or fitting, difficulty in finding words, hanging while talking, difficulty in understanding, impairment of attention and concentration, disturbance in visual-spatial perception, time and place orientation, to be lost are usual findings. There may be lack of cleaning, house arrangement, body care, difficulty in selecting clothes summer-winter, dirty-clean mixing, difficulty in food preparation, dressing, washing and eating.
There are two reasons for dementia:
1
* atAmmonia formed during the breakdown of proteins in the intestines is normally converted to uric acid and removed from the kidneys. If the ammonia produced is excessive than the liver can break down, accumulated ammonia is carried to the brain. The astrocytic cells present in the system convert ammonia to glutamine and allow it to be removed. As the age progresses, this process gradually slows down and causes the accumulation of ammonia to initiate the development of dementia symptoms. At the same time arginine amino acid deficiency occurs. The destruction of astrocytes is weakening the immune system of the brain. Degenerative changes develop in neurons and cause Alzheimer's disease.
* Bonzai - cocaine - alcohol-related substance dependence causes excess glutamate accumulation which results cell death and Alzheimer's can occur.
* Free radicals formed during oxidative metabolism cause neurodegeneration in Alzheimer's disease.As is known, the brain is sensitive to oxidative stress.. In such a case, DNA degradation, damage to the membranes and neuronal cell death occur.
2 Nerve cells are intact, malignacy, head trauma, vascular pathologies.
Oxygenation and glucose deficiency arise due to inadequate brain blood flow.The level of dopamine, noradrenalin, and serotonin is low in Alzheimer's. These deficiencies include sleep problems, depression, appetite, agitation, and psychotic statements.
TREATMENT
Therapy must aim the removal of cause.
Commonly used drug treatments purpose to reduce glutamate excess in the brain and eliminate acetylcholine deficiency
An ideal treatment;
1) Reduce the production of ammonia in the intestines and clean up the accumulation in the head.
2) Stop and repair degenerative changes in nerve cells
Under Construction
