It's a disease that can hold the entire digestive tract. The type seen in the small intestine is called Crohn. The surface of the small intestine mucosa is 800 square meters, a stadium size. There is a M neuroanal receptor in every square millimeter of this large area. The number of nerve cells in the small intestine is more than the brain. For this reason, the intestine is called as secondary brain. These M nerve endings test the foods to be absorbed. In healthy humans, this test prevents harmful foods to the body. However, in Crohn's disease, the body's immune system recognise the lower layer of the intestinal mucosa as foreign matter and attacks it. This is called autoimmune disease. In this case, mucosal widespread inflammation and ulcers occur in the intestines. The permeability of the intestinal wall deteriorates. Bleeding, gas, severe abdominal pain, diarrhea, blood in stool are common. In later stages, narrowing and obstruction of the intestine, fistula, pain in the joints, skin lesions may occur., Weight loss, anemia, loss of appetite, fatigue occurs in a short term. How is Crohn's disease treated?
Commonly applied treatments are drugs such as salozopyrine and salofoquin which suppress inflammatory reaction. In more worse patients, cancer drugs such as methotrexate and cortisone as an immune suppressant, block the immune system function. However, these treatments can not provide a permanent improvement, since the cause of disease has not been elimnated. Because the real problem is not in the immune system, but in the submucosa of the small intestine. The immune complex molecules that accumulate in the submucosa show it as the wrong target.
An ideal treatment method:
* immune complex accumulation in the submucosa should be eliminated
* Rebuilding should be prevented,
* The small intestine should function normally after being repaired the damage that occurs in the mucsal membrane,.
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